I have not tried the H&N slugs yet but have tried about everything else. I have yet to find a slug that will match the accuracy of the 33.95 grain pellets at 100 yards.
Can't speak for the .25 but my RAW .30 loves the NSA 50 gr HP-DB all the others are just ok. I have shot hundreds of prairie dogs between 100 and 277 yds with them. I do not see a DB in the .25 but there was a noticeable difference between the FB and the DB in my gun. I would talk to Nick and get a sample pack of the .25s and see if one fits the bill.
I’ve been shooting a whole bunch of .25 cal Nielsen dish based and flat base slugs in lighter weights. They are available and more will be shortly. The 29gr is a dish base!