I have to disagree. Right now there is .177, .20, .22, .25, .30, .357, .45, .50. There's a choice for everyone and task. When I was a kid there was .177 and .22 - the choices only get bigger, not smaller. Unless a particular caliber (ahem .20 - don't hate me) that is really niche and it becomes hard to obtain (or have a decent selection of) ammo for it.
Power's fun but not everything. I got into PCP for simple, consistent and precise power. But just by grabbing any of 6 or 7 airguns I can go from 6fpe to 800+ fpe.
One other to consider is energy transfer to the target and pass through (if you're a hunter). My guess would be if you put a 60 fpe .22 up against a 60 fpe .30, the .30 will be able to transfer more energy to the target.
edit:
I just thought to add that if we are talking purely longer range target shooting I'll take a smaller caliber that can push serious power.