When going for a significant detune, simply backing off the hammer spring preload will produce a high extreme spread. What happens is you're gradually moving toward a state of valve lock where the hammer is barely able to knock open the valve.
However for short distances, say inside of 20-30 yards, a large spread may be of no consequence. There is also an upside...very short valve dwell makes it very quiet and very efficient. For inside a barn, that may be an excellent choice.
For example, one time I dialed a 30fpe .22 down to 13fpe for a little gray squirrel cull in the suburbs. All the shots were to be inside of the owner's fenced back yard with a maximum distance of 30 yards. That morning the rifle went 6 for 6 and it was so quiet that the neighbors didn't notice...and neither did the squirrels.
If you're interested in maintaining a tight ES, look at either restricting the transfer port or doing as you said, reduce the regulator's setpoint (and back off the hammer spring accordingly).