The main thing is probably to determine at what ranges you will be shooting the most.
One neat help for your setup is this:
The ballistic calculator John mention above (ChairGun) for either a PC or Android/iPhone has a function that calculates your ideal zero point (another mobile app, Strelok Pro, has the same function, very cool

).
Enter your basic data: pellet, muzzle velocity, scope height.
Then decide how large of a target you want to hit, say 1" is the size of your "bulls' eye", and enter that.
Then the app will calculate for you
the zero point where you can
get the largest PBR (point blank range), i.e., the longest stretch where you can put the crosshairs on the target without holdovers or turret dialing and still hit within the 1" of your bulls' eye.
Of course, if the calculator spits out that your zero should be at 40y and that your PBR is from 16y to 45y — but you only have 15y of range in your backyard, then this whole thing makes no sense....!
The less power your gun has, or the heavier your pellet is, the shorter is the PBR.
Matthias