I was informed I could shoot slugs out of my .22 gauntlet. I tried several different sizes of NSA slugs without good luck. Never tried any other brands. Recently sold the gun to a friend so i can't try the FX slugs that are giving me good results out of another gun. Your results may vary.
Just getting into tuning myself, and I am finding that hammer spring settings have a lot to do with slug accuracy and the efficiency of the gun when shooting slugs. The gauntlet does not have an externally adjustable HS or regulator. However, Hajimoto has several videos (youtube) that show how to drill the rear of the stock for HS adjustment without removing the stock for each adjustment. He also sells other hammer springs, poppets and washers that can adjust the regulator. I'm definitely not experienced at tuning, but with some help from the forums and members here, you will be on the right track.