From what I have heard the .25 and .30 are supposed to shoot better in the wind BUT...I will stick with .22. The caliber had proven to be accurate and their seems to be more choices of ammo and it's cheaper to shoot and you get more shots per fill. If I do my part as well as my rifle, I have no regrets shooting my .22 against the .25 or the .30 caliber's. The fact that a .25 or .30 will hit harder can't be argued, but a miss in any caliber is still a miss. ANY caliber you choose with the right shooter, rifle, and ammo will perform. Get what you want...and practice.