@.20calguy said earlier; "I generally have contrasting backgrounds to help with visibility."@maxtrouble I am using a Holosun 507c reflex sight. I have not used other models or dots. I take a break when I reload or finish a group (5, 8, or 9 shots). When I can see the holes from where I’m standing I will move the pistol to view the target to be sure I’m close to my POA. I will shoot 2 or 3 shots at close intervals sometimes. At other times I shoot slowly shot by shot focusing on my breathing and trigger “pull.“ I tend to shoot the pistol later in the evening around sunset shooting towards the horizon with the setting sun behind the tree-line.
The olympic shooters seem to all have a black background / wall, then a black box with a white square target paper with a black target area.
Have you tried a different shooting setup? Maybe those hot rod pistol shooters know something. I bought a stack of these to shoot at in my basement. I have this target at about 28 feet and I do not experience eye fatigue.

10 Meter Air Pistol Targets (1000/pk) — Kruger Premium Targets
Article number: 3000 10 Meter Air Pistol Target Distance: 10 meters Size: 6.69” x 6.69” Packing unit: 1000 targets
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