I have a Crown MK2 that was originally a .25 380mm and it is currently set up as a .22 380mm. It shoots everything I've fed it very, very accurately from 14.3 gr .22 Crosmans to .25 26gr slugs. I have a 90 yard range at my house, and if there's no wind, it will shoot the .22 Crosman domes at 90 yards accurately. It loves 18 grain JSB's. I also have the 500mm barrels in .25 and .22, and I find they are faster, but no more accurate, and for me the trade off for extra length is not really worth it. I also have the arrow barrel for it, and it's amazing. For hunting, I really like the .25, but everything is covered with snow where I live, most of the critters are in hibernation, and with the pellet situation, I am primarily shooting the Crosmans until spring. My reg is at 150, and I just keep it there and spin the power wheel for different pellets and slugs in both .22 and .25.
It is probably the one gun I would keep if I had to sell all my others.