What are you trying to accomplish?
I have a Continuum (Mk1) in .25/6.35 and I have always left the transfer port wheel on the .25/.30 setting. I have only done chrono testing with a couple of different pellet weights, and at different hammer spring settings. My reg is also set (factory?) at about 135 bar, but these numbers are with the 700mm superlight barrel.
Crown Continuum 700mm Barrel .25