I use them on many of my guns, they are generally moderator safe, I use them in several different moderated guns. I generally use them dry, after cleaning the barrel with a boresnake or similar cleaning method. Some moderators have closer tolerances than mine, so care should be taken to make sure the cleaning pellet makes it out. Even if it don't, it should not damage any internal parts. Worst case scenario is you'll have to remove the moderator and possibly take it apart to get it out if it does get stuck.