I shot my first magpie with a .25cal today (first anything that wasn't paper). Based on the sound on impact and how it dropped I would say the 25gr .25cal hits harder than the 25gr .22cal Redesigned I was using last year. It makes sense as there is more surface area on the pellet that makes contact. The velocity of the .25cal pellet was slower than the .22cal Redesigned I was shooting last year. 28fpe vs 40fpe at 30 yards as per Strelok Pro.
https://www.youtube.com/watch?v=f10eHxVPlLs
https://www.youtube.com/watch?v=f10eHxVPlLs