Vana2 - Your first paragraph was the most important: "my applications – target; plinking; pesting and small game hunting (in that order)"
We all want the universal gun that does it all perfectly, but that gun doesn't exist, so this whole crazy sport is really just many compromises that we hope performs well.
I have a .22 Marauder and a .25 Impact. Next gun (Probably another Impact) will probably be a .22 because of economy over a .30 or other larger caliber. I mostly punch holes in paper and a .22 does that quite well unless wind is involved, then the larger calibers seem to work better. .22 is a third cheaper on ammunition costs, uses less air, quieter, etc. These are important factors for me.
Other advantage to a .22 is that more people shoot it. It's more common so new improvements often come out in .22 before other calibers.
I punch paper, I plink, very little pesting and hunting, so for me, a .22 is a better choice. I hope it works out that way for you as well.